Selank
Also known as: TP-7, Selank nasal spray, Tuftsin analog
Russian-developed anxiolytic and cognitive enhancer — anti-anxiety without sedation or dependence.
Molecular structure image coming soon
Research use only in the US. Approved in Russia. Not scheduled/controlled in US. Consult physician for anxiety treatment.
Overview
Selank is a synthetic heptapeptide analog of tuftsin, developed by the Institute of Molecular Genetics of the Russian Academy of Sciences. It is approved in Russia for anxiety, asthenic conditions, and immunodeficiency. It has anxiolytic effects comparable to benzodiazepines without sedation, dependence potential, or cognitive impairment. Also demonstrates memory enhancement and nootropic properties.
Mechanism of Action
Selank modulates the expression of GABA-A receptor subunits, producing anxiolytic effects through GABAergic pathways. It also increases BDNF expression (brain-derived neurotrophic factor), modulates monoamine neurotransmitters (serotonin, dopamine), and has anti-inflammatory properties via cytokine modulation.
Use Cases
- ✓Anxiety and stress reduction
- ✓Cognitive enhancement and memory
- ✓Depression (as adjunct)
- ✓Immune system modulation
- ✓ADHD and focus improvement
Research Summary
Approved and widely prescribed in Russia. Multiple published Russian clinical trials demonstrate efficacy for generalized anxiety disorder, phobias, and asthenic conditions with excellent tolerability. Animal studies consistently show memory enhancement and anxiolytic effects without dependence.
Typical Dosing
250–3000 mcg intranasal (most common) or subcutaneous. Nasal spray allows easy dosing.
Administration
Research Chemical
Research use only in the US. Approved in Russia. Not scheduled/controlled in US. Consult physician for anxiety treatment.
