Ipamorelin
Also known as: NNC 26-0161
The cleanest GH secretagogue — selective growth hormone release with minimal side effects.
Molecular structure image coming soon
Research use only. Not FDA-approved. Best used under medical supervision with IGF-1 monitoring.
Overview
Ipamorelin is a selective Growth Hormone Secretagogue (GHS) and ghrelin receptor agonist. It is widely considered the most selective GHRP available, stimulating GH release without significantly elevating cortisol or prolactin — making it the preferred option for those concerned about side effect profiles. Most commonly paired with CJC-1295 (no DAC).
Mechanism of Action
Ipamorelin mimics ghrelin and binds to the GHS receptor (ghrelin receptor) in the pituitary and hypothalamus, stimulating growth hormone release. Unlike other GHRPs, it has high selectivity and does not cause significant cortisol, prolactin, or ACTH elevations.
Use Cases
- ✓Growth hormone optimization
- ✓Lean muscle development
- ✓Fat loss acceleration
- ✓Improved sleep quality
- ✓Recovery and anti-aging
- ✓GH deficiency protocols
Research Summary
Multiple clinical studies confirm ipamorelin's potent and selective GH-releasing activity. It produces a dose-dependent increase in GH without the cortisol and prolactin spikes seen with other GHRPs. The CJC-1295 + Ipamorelin combination is among the most prescribed peptide protocols in anti-aging medicine.
Typical Dosing
100–300 mcg 2–3x daily, typically at night 30–60 minutes before sleep on empty stomach. Often stacked with CJC-1295 (no DAC).
Administration
Research Chemical
Research use only. Not FDA-approved. Best used under medical supervision with IGF-1 monitoring.
