Hexarelin
Also known as: Examorelin, MF-6003
The most potent GHRP — maximum GH release with added cardioprotective properties.
Molecular structure image coming soon
Research use only. Not FDA-approved. Causes more cortisol and prolactin elevation than ipamorelin.
Overview
Hexarelin is a potent synthetic hexapeptide and Growth Hormone Releasing Peptide (GHRP). It is considered one of the most potent GHRPs available, producing robust GH release. Unlike other GHRPs, hexarelin also exerts direct cardioprotective effects through CD36 receptor binding, independent of GH release.
Mechanism of Action
Hexarelin activates ghrelin/GHS receptors in the pituitary and hypothalamus for GH release. Additionally, it binds CD36 receptors in cardiac tissue, providing direct cardioprotective effects including improved heart function and protection against ischemic damage.
Use Cases
- ✓Maximum GH stimulation
- ✓Cardiac protection and recovery
- ✓Muscle and strength development
- ✓Recovery from cardiac events (emerging research)
Research Summary
Studies show hexarelin produces the highest acute GH release among GHRPs. Cardiac studies demonstrate significant improvements in ventricular function and protection against ischemic injury. Note: tachyphylaxis (reduced response) develops faster with hexarelin than other GHRPs, requiring cycling protocols.
Typical Dosing
100–200 mcg 2–3x daily. Should be cycled (4–6 weeks on, 2–4 weeks off) to prevent desensitization.
Administration
Research Chemical
Research use only. Not FDA-approved. Causes more cortisol and prolactin elevation than ipamorelin.
