Epithalon
Also known as: Epitalon, Epithalone, Epithalamin, Tetrapeptide ALA-GLU-ASP-GLY
The telomere peptide — restores telomerase activity for cellular aging reversal.
Molecular structure image coming soon
Research use only. Not FDA-approved. Long-term human safety data primarily from Russian research.
Overview
Epithalon is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed by the St. Petersburg Institute of Bioregulation and Gerontology. Based on the endogenous thymic peptide Epithalamin, it is one of the most studied longevity peptides with over 100 studies and 40+ years of research. It activates telomerase, lengthens telomeres, and has demonstrated life extension in animal models.
Mechanism of Action
Epithalon activates the enzyme telomerase (which extends telomeres — the protective caps at the ends of chromosomes that shorten with age), normalizes pineal gland function and melatonin production, modulates cortisol/TSH levels, and exerts antioxidant and anti-tumor properties.
Use Cases
- ✓Telomere restoration and anti-aging
- ✓Sleep quality improvement
- ✓Immune system regulation
- ✓Antioxidant protection
- ✓Hormonal normalization in aging
- ✓Cancer prevention (preclinical research)
Research Summary
Over 100 published studies, primarily from Russian and Ukrainian institutes. Multiple animal studies demonstrate 24–33% life extension. Human studies show improvements in biomarkers of aging, improved sleep, immune function, and antioxidant capacity. One of the few peptides with genuine telomerase activation evidence in humans.
Typical Dosing
5–10 mg/day for 10–20 day cycles, 2x per year. Subcutaneous or IV. Some protocols use every-other-day dosing.
Administration
Research Chemical
Research use only. Not FDA-approved. Long-term human safety data primarily from Russian research.
